NEW STEP BY STEP MAP FOR AZELAPRAG SMALL MOLECULE

- "Tolvaptan is approved for ADPKD treatment, but its use is limited by several adverse effects, leaving an unmet clinical need for safe and effective therapy.Powerful cytochrome P450 3A4 and/or P-glycoprotein inhibitors may warrant AMG 986 dose reduction and should be coadministered with caution in patients with heart failure handled with AMG 986.